[AUDITORY] Auditory cortex data, time-warped spike time patterns, high trial counts

Subject: [AUDITORY] Auditory cortex data, time-warped spike time patterns, high trial counts

From: James Bryden Isbister <0000029f9dac1ab6-dmarc-request@xxxxxxxxxxxxxxx>

Date: Wed, 10 Jan 2024 10:04:38 +0000

Accept-language: en-GB, fr-CH, en-US

Arc-authentication-results: i=1; mx.google.com; dkim=pass header.i=@LISTS.MCGILL.CA header.s=SELECTOR1 header.b="kaOb/rUM"; spf=pass (google.com: domain of owner-auditory@xxxxxxxxxxxxxxx designates 132.206.27.104 as permitted sender) smtp.mailfrom=owner-auditory@xxxxxxxxxxxxxxx; dmarc=pass (p=NONE sp=NONE dis=NONE) header.from=mcgill.ca

Arc-message-signature: i=1; a=rsa-sha256; c=relaxed/relaxed; d=google.com; s=arc-20160816; h=list-archive:list-owner:list-subscribe:list-unsubscribe:list-help :precedence:to:subject:from:sender:reply-to:date:message-id :mime-version:content-language:accept-language:thread-index :thread-topic:approved-by:dkim-signature; bh=qn5NQcnrnMShfD5AM86DAHQcS1LVYUQD11sxG/4fut0=; fh=5/42mu9FVmfuMp6n0xGXVcDar2H3ENcHt8Uv11Om8gY=; b=Dqk1iBpl/7oail+JscNRzAxYzGtz9KjZ9O4Cog/4G2O6zweAa26fm72rvX0YQJJRJK RklmpuIS1T2lMunqT+ltFRRsLvLJ3MOONGj0+mZkBN2c0U4X1Q90AHiv9GSDZ4TILTI4 kqwLKJCVK1KKs4wo4bO/P+psBnk4kKMa6UEyr2zEwdi3nbUJjWbLjUk5nF1cGKkVvSB4 rhlf/dAYXIkVxklaUoLB9CBGfofHKG2PW9mGN4TyRdSePb89KKoWKD16iMWDf2E1CfmI IyQGcAleTPr+9+DC46lh1uPdcHhqLj4OmwzubZWHqha6y8Xelpd4CwcqDV8LwcHZLGrY XEpA==

Arc-seal: i=1; a=rsa-sha256; t=1704885273; cv=none; d=google.com; s=arc-20160816; b=vtg84oKcHoCBgeggEAtr2Rr26sf8iIVPcCkH2H5KraVMZUvLFJh5gLKZ6KNpzOlNUF rONFxyWGD1OJVb7/41eYys7XAVmWT5qMbxnaQCaCchwtqlbmTiFcgG+MqxmsvQca1G3J AwkybMxn6p7pob9m5ClWtZQxigT1SoZ1Ni/9MeZub82JQWah4i0xk9bkRFP744GTtwzO OGOeYyATNUWE23hmsnvMOPZwtpAkdtH1VtmdqBuiRuh/IJsYLKOEvFWhTpCwp7CpviZ1 cNpiKPvXW8DGWsFlntITKAbgrpGLfnIAiIiI3zp4IxQTBKc7SsrVBVr+Pe0tL12UZqav I6dQ==

Authentication-results: mx.google.com; dkim=pass header.i=@LISTS.MCGILL.CA header.s=SELECTOR1 header.b="kaOb/rUM"; spf=pass (google.com: domain of owner-auditory@xxxxxxxxxxxxxxx designates 132.206.27.104 as permitted sender) smtp.mailfrom=owner-auditory@xxxxxxxxxxxxxxx; dmarc=pass (p=NONE sp=NONE dis=NONE) header.from=mcgill.ca

Delivered-to: dan.ellis@xxxxxxxxx

Dkim-signature: v=1; a=rsa-sha256; d=LISTS.MCGILL.CA; s=SELECTOR1; c=relaxed/relaxed; bh=qn5NQcnrnMShfD5AM86DAHQcS1LVYUQD11sxG/4fut0=; i=@LISTS.MCGILL.CA; h=Approved-By:Thread-Topic:Thread-Index:Accept-Language:Content-Language:Content-Type:MIME-Version:Message-ID:Date:Reply-To:Sender:From:Subject:To:List-Help:List-Unsubscribe:List-Subscribe:List-Owner:List-Archive; b=kaOb/rUMNuaJg+MmRV9woIqc7SgYlMxllOzjdMUcMIjgsERNBO4j0S4DzByZ6fZfXHaO/ZC+Jib/c3DlKfurCVok3VUrj9EGndwBPllnJ4czbRK+jPEISK0olvLLq65CJNseTdGoG/7iLHV9+m3LvYXaVWlPqIG/Weh6lyQWtc8o6eCBTXhb0TGCswC1kZ0uoItrfZwClAZXhYqxJw1BmsArx0XWsEdie2b/2woatHxMP9veuUxfNayHq0XOPWJsYPRQBRrOCImVyIAzMDLulKzST6inqaoGI2cR+PPibk25OgXatXSaqeOfV8buwpO6qUxNdCkkGgctM8A2StXdNA==

List-archive: <https://lists.mcgill.ca/scripts/wa.exe?LIST=AUDITORY>

List-help: <https://lists.mcgill.ca/scripts/wa.exe?LIST=AUDITORY>, <mailto:LISTSERV@LISTS.MCGILL.CA?body=INFO%20AUDITORY>

List-owner: <mailto:AUDITORY-request@LISTS.MCGILL.CA>

List-subscribe: <mailto:AUDITORY-subscribe-request@LISTS.MCGILL.CA>

List-unsubscribe: <mailto:AUDITORY-unsubscribe-request@LISTS.MCGILL.CA>

Reply-to: James Bryden Isbister <james.isbister@xxxxxxx>

Sender: AUDITORY - Research in Auditory Perception <AUDITORY@xxxxxxxxxxxxxxx>

Thread-index: AQHaQ6xsV0yg/JAyskmnRrxU49ubsQ==

Thread-topic: Auditory cortex data, time-warped spike time patterns, high trial counts

Dear all,

I am am a postdoc at EPFL in Switzerland and I’m looking for a spike sorted dataset from auditory cortex (ideally in awake animals) with a high number of repetitions per unique stimulus (i.e. 50-100+ trials per stimulus condition).

I would like to test for a phenomena that we previously characterised in the barrel cortex (under anesthetic). Particularly, we showed that millisecond precise spike time patterns representing the stimulus are obscured or rather “time-warped” (i.e. stretched/compressed) on each trial depending on the background activity level (https://www.nature.com/articles/s41598-021-94002-0). We suggest that these time-warped spike time patterns might be a ubiquitous and fundamental form of information representation across the cortex.

Auditory cortex provides an ideal model for extending these results to the awake case so please let me know if you have a dataset as described above. Please also reach out if you would like to discuss the concept or might be interested in running a small pilot study to test for the phenomena. I’m also looking to give talks on the subject.

Best wishes,

James

James Isbister
Postdoctoral Researcher
Blue Brain Project / EPFL

Campus Biotech
Chemin des Mines 9
CH-1202 Geneva
+447454 363444

https://www.epfl.ch/research/domains/bluebrain/james-b-isbister

portal.bluebrain.epfl.ch/

Follow BBP on Twitter - @BlueBrainPjt

Connect on LinkedIn - linkedin.com/showcase/blue-brain-project