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Re: aspirin and loud noises

I believe what you want is research into the use of antioxidants to
ameliorate and/or prevent hearing loss. Specifically, two antioxidants,
acetyl-L-carnitine (ALCAR) and N-L-acetylcysteine (NAC) have been of
interest to the military. 

This is not specifically my area, but a google search for antioxidants and
hearing loss prevention should get you started.

It is a bit controversial here because of the concern that people will fail
to wear hearing protection, thinking that a drug can fix things. That said,
there are many who are exposed to such high levels of noise that even
hearing protection is not sufficient.

-----Original Message-----
From: AUDITORY - Research in Auditory Perception
[mailto:AUDITORY@xxxxxxxxxxxxxxx] On Behalf Of Dan Stowell
Sent: Tuesday, May 06, 2014 6:16 AM
To: AUDITORY@xxxxxxxxxxxxxxx
Subject: aspirin and loud noises

Dear all,

I have a memory of a talk by Brian Moore, during which I think he mentioned
aspirin having a mild protective effect against hearing impairment from
acute loud noise.

However, I may have misremembered: now that I search the literature, I can't
find anything very definitive - and conversely, I find hints that aspirin
may long-term mildly contribute to hearing loss (e.g.
<http://europepmc.org/articles/PMC2831770>). I find some animal studies
pointing in the direction of the factoid I remember

Can anyone confirm/deny whether such a protective effect is expected?


Dan Stowell
EPSRC Research Fellow
Centre for Digital Music
Queen Mary, University of London
Mile End Road, London E1 4NS

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