[AUDITORY] Nottingham Hearing Sciences Seminar - Prof Dan Jagger - 24th February @xxxxxxxx 2pm (Joseph Sollini )

Subject: [AUDITORY] Nottingham Hearing Sciences Seminar - Prof Dan Jagger - 24th February @xxxxxxxx 2pm From: Joseph Sollini <Joseph.Sollini@xxxxxxxx> Date: Thu, 17 Feb 2022 16:07:50 +0000 --_000_AM9PR06MB81483D01C1BCEB05226EA346C5369AM9PR06MB8148eurp_ Content-Type: text/plain; charset="us-ascii" Content-Transfer-Encoding: quoted-printable Dear All, I am delighted to confirm our next speaker in the Hearing Sciences Seminar = Series is Professor Dan Jagger, a Professor in Cell Physiology at the UCL E= ar Institute, who will be giving the following talk (@xxxxxxxx on Thursday the 2= 4th of February): "Roles for inner ear connexins in health and disease" Abstract: The normal development, function and repair of inner ear sensory epithelia = are dependent on gap junctional communication. Gap junctions are intercellu= lar membrane channels connecting adjacent cells and are constructed from co= nnexin protein subunits. Connexin 26 (Cx26) and Cx30 are widely expressed i= n the epithelial and connective tissues of the cochlea, where they may form= homomeric or heteromeric gap junction channels in a cell-specific and spat= iotemporally complex fashion. Mutations in the connexin genes GJB2 and GJB6= (encoding Cx26 and Cx30) result in syndromic and non-syndromic deafness vi= a various mechanisms. In this seminar I will review the proposed roles for = gap junctions in normal auditory function, and our current understanding of= how connexin mutations result in hearing loss. Biography: Dan Jagger is Professor of Cell Physiology at the UCL Ear Institute. Follow= ing a BSc at the University of Newcastle Upon Tyne he completed his PhD in = Jonathan Ashmore's lab at the University of Bristol. Following postdocs at = UCL and the University of Auckland he held a Royal Society University Resea= rch Fellowship at the UCL Ear Institute (2003-2011), and has remained there= since. His lab currently studies questions of inner ear homeostasis, neuro= nal signalling, and hair cell development. Best wishes, Joe ___________________________________________________________________________= _____ Microsoft Teams meeting Join on your computer or mobile app Click here to join the meeting<https://teams.microsoft.com/l/meetup-join/19= %3ameeting_OGRhZmU2M2YtZWU5YS00YzNiLWFkYjUtYzIwODJhOTAwNTky%40thread.v2/0?c= ontext=3D%7b%22Tid%22%3a%2267bda7ee-fd80-41ef-ac91-358418290a1e%22%2c%22Oid= %22%3a%22a04db259-744c-438c-a55a-fcb9a68bc359%22%7d> Learn More<https://aka.ms/JoinTeamsMeeting> | Meeting options<https://teams= .microsoft.com/meetingOptions/?organizerId=3Da04db259-744c-438c-a55a-fcb9a6= 8bc359&tenantId=3D67bda7ee-fd80-41ef-ac91-358418290a1e&threadId=3D19_meetin= g_OGRhZmU2M2YtZWU5YS00YzNiLWFkYjUtYzIwODJhOTAwNTky@xxxxxxxx&messageId=3D0&= language=3Den-US> Dr Joseph Sollini Auditory Circuits Lab Hearing Sciences Mental Health and Clinical Neuroscience, School of Medicine The University of Nottingham W: https://www.nottingham.ac.uk/research/groups/hearingsciences/people/jose= ph.sollini W: https://orcid.org/0000-0002-1974-4291 This message and any attachment are intended solely for the addressee and may contain confidential information. If you have received this message in error, please contact the sender and delete the email and attachment.=20 Any views or opinions expressed by the author of this email do not necessarily reflect the views of the University of Nottingham. Email communications with the University of Nottingham may be monitored=20 where permitted by law. --_000_AM9PR06MB81483D01C1BCEB05226EA346C5369AM9PR06MB8148eurp_ Content-Type: text/html; charset="us-ascii" Content-Transfer-Encoding: quoted-printable <html xmlns:v=3D"urn:schemas-microsoft-com:vml" xmlns:o=3D"urn:schemas-micr= osoft-com:office:office" xmlns:w=3D"urn:schemas-microsoft-com:office:word" = xmlns:m=3D"http://schemas.microsoft.com/office/2004/12/omml" xmlns=3D"http:= //www.w3.org/TR/REC-html40"> <head> <meta http-equiv=3D"Content-Type" content=3D"text/html; charset=3Dus-ascii"> <meta name=3D"Generator" content=3D"Microsoft Word 15 (filtered medium)"> <style></style> </head> <body lang=3D"EN-GB" link=3D"#0563C1" vlink=3D"#954F72" style=3D"word-wrap:= break-word"> <div class=3D"WordSection1"> Dear All,<o:p></o:p>  <o:p></o:p> I am delighted to confirm our next speaker in the H= earing Sciences Seminar Series is Professor Dan Jagger, a Professor in Cell= Physiology at the UCL Ear Institute, who will be giving the following talk= (@xxxxxxxx on Thursday the 24th of February):<o:p></o:p>  <o:p></o:p> “Roles fo= r inner ear connexins in health and disease”<o:p></o:p>  <o:p></o:p> Abstract:</span= > <= /span><o:p></o:p> T= he normal development, function and repair of inner ear sensory epithelia a= re dependent on gap junctional communication. Gap junctions are intercellul= ar membrane channels connecting adjacent cells and are constructed from connexin protein subunits. Connexin 26 (Cx2= 6) and Cx30 are widely expressed in the epithelial and connective tissues o= f the cochlea, where they may form homomeric or heteromeric gap junction ch= annels in a cell-specific and spatiotemporally complex fashion. Mutations in the connexin genes GJB2 and GJB6 (encoding C= x26 and Cx30) result in syndromic and non-syndromic deafness via various me= chanisms. In this seminar I will review the proposed roles for gap junction= s in normal auditory function, and our current understanding of how connexin mutations result in hearing loss= . </spa= n><o:p></o:p>  <o:p></o:p> Biography: <o:p></o:p> D= an Jagger is Professor of Cell Physiology at the UCL Ear Institute. Followi= ng a BSc at the University of Newcastle Upon Tyne he completed his PhD in J= onathan Ashmore’s lab at the University of Bristol. Following postdocs at UCL and the University of Auckland he he= ld a Royal Society University Research Fellowship at the UCL Ear Institute = (2003-2011), and has remained there since. His lab currently studies questi= ons of inner ear homeostasis, neuronal signalling, and hair cell development.<= span style=3D"color:black"> <o:p></o:p>  <o:p></o:p> Best wishes,<o:p></o:p> Joe<o:p></o:p>  <o:p></o:p>  <o:p></o:p> _____________________= ___________________________________________________________ <o:p></o:p> Microsoft Teams meet= ing <o:p></o:p> Join on your comp= uter or mobile app <o:p></o:p> <a href=3D"https://teams.microsoft.co= m/l/meetup-join/19%3ameeting_OGRhZmU2M2YtZWU5YS00YzNiLWFkYjUtYzIwODJhOTAwNT= ky%40thread.v2/0?context=3D%7b%22Tid%22%3a%2267bda7ee-fd80-41ef-ac91-358418= 290a1e%22%2c%22Oid%22%3a%22a04db259-744c-438c-a55a-fcb9a68bc359%22%7d" targ= et=3D"_blank">Click here to join the meeting</a> <o:p></o:p> <a href=3D"https://aka.ms/JoinTeamsMe= eting" target=3D"_blank">Lea= rn More</a> | <a href=3D"https://teams.microsoft.com/meetingOptions/?organizerId=3Da04db2= 59-744c-438c-a55a-fcb9a68bc359&tenantId=3D67bda7ee-fd80-41ef-ac91-35841= 8290a1e&threadId=3D19_meeting_OGRhZmU2M2YtZWU5YS00YzNiLWFkYjUtYzIwODJhO= TAwNTky@xxxxxxxx&messageId=3D0&language=3Den-US" target=3D"_blank"> Meeting options</a> <= /span><o:p></o:p> <o:p> </o:p> <o:p> </o:p> Dr Joseph Sollini<o:p></o:p> Auditory Circuits Lab<o:p></o:p> Hearing Sciences<o:p></o:p> Mental Health and Clinical Neuroscience, School of Medicine<o:p></o:p>= The University of Nottingham<o:p></o:p> <o:p> </o:p> W: <a href=3D"https://www.nottingham.ac.uk/research/groups/hearingscie= nces/people/joseph.sollini"> https://www.nottingham.ac.uk/research/groups/= hearingsciences/people/joseph.sollini</a><o:p></o:p> W: <a href=3D"https://orcid.org/0000-0002-1974-4291"> https://orcid.org/0000-0002-1974-4291<= /a><o:p></o:p> <o:p> </o:p> </div> <PRE> This message and any attachment are intended solely for the addressee and may contain confidential information. If you have received this message in error, please contact the sender and delete the email and attachment.=20 Any views or opinions expressed by the author of this email do not necessarily reflect the views of the University of Nottingham. Email communications with the University of Nottingham may be monitored=20 where permitted by law. </PRE></body> </html> --_000_AM9PR06MB81483D01C1BCEB05226EA346C5369AM9PR06MB8148eurp_--

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