Postdoctoral Research Position at Washington University in St. Louis (Gabrielle Merchant )


Subject: Postdoctoral Research Position at Washington University in St. Louis
From:    Gabrielle Merchant  <grmerchant@xxxxxxxx>
Date:    Fri, 15 Jul 2016 15:07:28 -0400
List-Archive:<http://lists.mcgill.ca/scripts/wa.exe?LIST=AUDITORY>

--Apple-Mail=_413D19A6-0E38-49E9-AEA4-99665948036C Content-Transfer-Encoding: quoted-printable Content-Type: text/plain; charset=utf-8 Posting on behalf of Jeffery T. Lichtenhan, PhD, Assistant Professor of = Otolaryngology at Washington University School of Medicine. All = correspondence regarding the position should be sent directly to him = (please do not reply to this email) at: LichtenhanJ@xxxxxxxx = <mailto:LichtenhanJ@xxxxxxxx> =20 Postdoctoral Research Position at Washington University in St. Louis We are seeking a fulltime postdoctoral researcher to help with ongoing = experiments in our laboratories. MDs, PhD, or AuDs are encouraged to = apply. Our research questions address the origin of objective = measurements from the ear. Objective measurements are routinely used to = study cochlear physiology and identify hearing loss, but their origins = remain uncertain. Understanding their origins will improve their = usefulness in basic and clinical applications. Several of our current studies use a variety of cochlear manipulations = to determine the origin along the cochlear spiral of reflection-source = otoacoustic emissions components with various latencies. One of our = technical innovations allows sequential drug delivery to finely spaced = cochlear regions using slow drug injection into the cochlear apex. This = technique is designed to overcome concentration losses associated with = classical round window drug delivery. Another study addresses a = long-standing question of high scientific and clinical interest that = still does not have an answer: What is the origin of low-frequency = hearing loss in ears with permanent endolymphatic hydrops? A innovation = associated with this study overcomes a long standing obstacle in = obtaining gross neural measurements at frequencies below 1 kHz, the = region affected by hydrops, by using our recently developed measurement = technique: the =E2=80=9CAuditory Nerve Overlapped Waveform=E2=80=9D = (ANOW).=20 Our experiments use animal models. We will provide the necessary = training for surgical techniques. A background in computer programing = would be beneficial, but an enthusiasm to learn would be terrific if you = do not have experience. Your primary role will be to make recordings and = preliminarily analysis of a variety of measurements using customized = data acquisition rigs and to participate in writing manuscripts.=20 Washington University in St. Louis has a long history of making = contributions to the field of hearing and vestibular science. Our = Department of Otolaryngology is currently growing. It=E2=80=99s a = friendly and exciting atmosphere to do research, and provides a good = sense of community. You may have additional opportunities to get = involved with our ongoing collaborations that make objective = measurements from the human ear during surgeries in the operating room = with Professor and Chair Craig A. Buchman MD FACS, studies on the = pharmacokinetics of inner-ear therapeutics with Professor Alec N. Salt = PhD, and studies of cochlear mechanics with Professor John J. Guinan Jr. = PhD.=20 Please send inquires and CVs to LichtenhanJ@xxxxxxxx = <mailto:LichtenhanJ@xxxxxxxx> --Apple-Mail=_413D19A6-0E38-49E9-AEA4-99665948036C Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset=utf-8 <html><head><meta http-equiv=3D"Content-Type" content=3D"text/html = charset=3Dutf-8"></head><body style=3D"word-wrap: break-word; = -webkit-nbsp-mode: space; -webkit-line-break: after-white-space;" = class=3D""><p class=3D"MsoNormal" align=3D"center" style=3D"text-align: = left; line-height: normal;">Posting on&nbsp;behalf of Jeffery T. = Lichtenhan, PhD, Assistant Professor of Otolaryngology at Washington = University School of Medicine. &nbsp;A<b class=3D"">ll correspondence = regarding the position should be sent directly to him (please do not = reply to this email) at</b>: <a href=3D"mailto:LichtenhanJ@xxxxxxxx" = class=3D"">LichtenhanJ@xxxxxxxx</a>&nbsp;&nbsp;</p><p = class=3D"MsoNormal" align=3D"center" style=3D"text-align: center; = line-height: normal;"><b class=3D""><br class=3D""></b></p><p = class=3D"MsoNormal" align=3D"center" style=3D"text-align: center; = line-height: normal;"><b class=3D"">Postdoctoral Research Position at = Washington University in St. Louis</b></p><p class=3D"MsoNormal" = align=3D"center" style=3D"text-align: center; line-height: normal;"><b = class=3D""><br class=3D""></b></p><p class=3D"MsoNormal" = style=3D"text-align: justify; line-height: normal;">We are seeking a = fulltime postdoctoral researcher to help with ongoing experiments in our = laboratories. MDs, PhD, or AuDs are encouraged to apply. Our research = questions address the origin of objective measurements from the = ear.&nbsp;Objective measurements are routinely used to study cochlear = physiology and identify hearing loss, but their origins remain = uncertain. Understanding their origins will improve their usefulness in = basic and clinical applications.</p><p class=3D"MsoNormal" = style=3D"text-align: justify; line-height: normal;"><br class=3D""></p><p = class=3D"MsoNormal" style=3D"text-align: justify; line-height: = normal;">Several of our current studies use a variety of cochlear = manipulations to determine the origin along the cochlear spiral of = reflection-source otoacoustic emissions components with various = latencies. One of our technical innovations allows sequential drug = delivery to finely spaced cochlear regions using slow drug injection = into the cochlear apex. This technique is designed to overcome = concentration losses associated with classical round window drug = delivery. Another study addresses a long-standing question of high = scientific and clinical interest that still does not have an answer: = What is the origin of low-frequency hearing loss in ears with permanent = endolymphatic hydrops? A innovation associated with this study overcomes = a long standing obstacle in obtaining gross neural measurements at = frequencies below 1 kHz, the region affected by hydrops, by using our = recently developed measurement technique: the =E2=80=9CAuditory Nerve = Overlapped Waveform=E2=80=9D (ANOW).&nbsp;<br class=3D""></p><p = class=3D"MsoNormal" style=3D"text-align: justify; line-height: = normal;"><br class=3D""></p><p class=3D"MsoNormal" style=3D"text-align: = justify; line-height: normal;">Our experiments use animal = models.&nbsp;We will provide the necessary training for surgical = techniques. A background in computer programing would be beneficial, but = an enthusiasm to learn would be terrific if you do not have experience. = Your primary role will be to make recordings and preliminarily analysis = of a variety of measurements using customized data acquisition rigs and = to participate in writing manuscripts.&nbsp;<br class=3D""></p><p = class=3D"MsoNormal" style=3D"text-align: justify; line-height: = normal;"><br class=3D""></p><p class=3D"MsoNormal" style=3D"text-align: = justify; line-height: normal;">Washington University in St. Louis has a = long history of making contributions to the field of hearing and = vestibular science. Our Department of Otolaryngology is currently = growing. It=E2=80=99s a friendly and exciting atmosphere to do research, = and provides a good sense of community. You may have additional = opportunities to get involved with our ongoing collaborations that make = objective measurements from the human ear during surgeries in the = operating room with Professor and Chair Craig A. Buchman MD FACS, = studies on the pharmacokinetics of inner-ear therapeutics with Professor = Alec N. Salt PhD, and studies of cochlear mechanics with Professor John = J. Guinan Jr. PhD.&nbsp;<br class=3D""></p><p class=3D"MsoNormal" = style=3D"text-align: justify; line-height: normal;"><br class=3D""></p><p = class=3D"MsoNormal" style=3D"text-align: justify;">Please send inquires = and CVs to&nbsp;<a href=3D"mailto:LichtenhanJ@xxxxxxxx" = class=3D"">LichtenhanJ@xxxxxxxx</a></p><br class=3D""> <br class=3D""></body></html>= --Apple-Mail=_413D19A6-0E38-49E9-AEA4-99665948036C--


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