Subject: Re: AUDITORY Digest - 6 Oct 2009 to 7 Oct 2009 (#2009-230) From: Jont Allen <jontalle@xxxxxxxx> Date: Thu, 8 Oct 2009 09:21:47 -0500 List-Archive:<http://lists.mcgill.ca/scripts/wa.exe?LIST=AUDITORY>Dear all, Three comments below. You will need to search for them. I get the digest version, so its all mixed together. Jont AUDITORY automatic digest system wrote: > There are 5 messages totalling 620 lines in this issue. > > Topics of the day: > > 1. Technique can pinpoint tinnitus (3) > 2. SOAEs and tinnitus (2) > > ---------------------------------------------------------------------- > > Date: Wed, 7 Oct 2009 18:43:36 +1100 > From: Andrew Bell <andrew.bell@xxxxxxxx> > Subject: Re: Technique can pinpoint tinnitus > > Matt and list: > > Thanks for pointer to Ceranic et al (1998), a paper which gives clear > evidence that spontaneous otoacoustic emissions (SOAEs) and tinnitus are > closely related. If SOAEs sound like tinnitus and behave like tinnitus, > isn't it likely that they are (in some respect) tinnitus? Sanity strikes. > If we are aiming to pinpoint tinnitus, then SOAEs offer the most direct > tool, and Ceranic et al. support this idea. Their Table 5 shows that > patients with head injury and tinnitus displayed 4.4 SOAEs per ear, = > compared > to 1.7 with normals and 0.25 with those having head injury without = > tinnitus. > > > So did the head injury damage the cochlea and generate a tinnitus = > sensation > (via afferent pathways), or did the injury damage the brain, which = > responded > by sending a signal to the cochlea (via efferent pathways)? As you say, = > that > question is still very much open, but it would definitely repay some > attention. > > > Andrew. > > > ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ > Andrew Bell > Research School of Biology (RSB) > The Australian National University > Canberra, ACT 0200, Australia > T: +61 2 6125 5145 > F: +61 2 6125 3808 > andrew.bell@xxxxxxxx > ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ > > > >> =20 >> Further, tinnitus can also be induced by head injury [6]. In=20 >> this case, it is possible that the inner ear is damaged and=20 >> this causes a peripheral type of tinnitus, which again is a=20 >> cochlear amplifier dysfunction. Until we can successfully=20 >> trace this cause and develop methods such as cellular=20 >> regeneration possibly using stem cells - we can tinker and=20 >> experiment using all sorts of procedures to quash the=20 >> problem, but they will never be as sophisticated as actually=20 >> repairing the biology. >> =20 >> =20 >> =20 >> [6] @xxxxxxxx{ceranic:1998, >> author =3D {Ceranic, B.J. and Prasher, D.K. and Raglan, E.=20 >> and Luxon, L.M.}, >> title =3D {{Tinnitus after head injury: evidence from=20 >> otoacoustic emissions}}, >> journal =3D {Journal of Neurology, Neurosurgery \& Psychiatry}, >> year =3D {1998}, >> volume =3D {65}, >> pages =3D {523--529}, >> number =3D {4}, >> publisher =3D {BMJ} >> } >> =20 > > ------------------------------ > > Date: Wed, 7 Oct 2009 11:24:06 -0400 > From: Didier Depireux <depireux@xxxxxxxx> > Subject: Re: Technique can pinpoint tinnitus > > The idea of the relationship between some measure from OAEs and > tinnitus is still progressing. Recently, Glenis Long and Lucas Parra > (and co-authors, sorry) gave very convincing evidence that even the > spectral profile of tinnitus, i.e. a tinnitus likeness spectrum, can > be predicted by measures of a high resolution audiogram and the growth > of DPOAE as a function of level. This was true for a subset of their > tinnitus sufferers, particularly those who have stable tinnitus. This is just one more paper in a long line, that shows the correlation between tinnitus and OAE. How about the one that started it all: http://auditorymodels.org/jba/PAPERS/Wegel31.djvu @xxxxxxxx{Wegel31 ,author={Wegel, R.L.} ,title={Study of tinnitus} ,journal="Archives Otolaryngology" ,year=1931 ,month=aug ,volume=14 ,pages={158-165} > However, remember that, as pointed out earlier by Arnaud in this > thread, people who have their 8th nerve resected (for surgical > resolution of a vestibular schwannoma, typically) often have tinnitus. This is a meaningless indicator. If you drive a truck over someone's head and crush their skull, they will become blind. Does it follow that you see with your skull? > The percentage depends a lot on which study you look at, but the point > is, you will typically get tinnitus once your cochlea is disconnected. > So OAEs won't be of much use at that point... > > Didier > > Didier A Depireux depireux@xxxxxxxx > Inst. for Systems Research http://theearlab.org > School of Engineering Ph: 410-925-6546 > U Md College Park MD 20742 USA > Adjunct, BioEngineering > > > > On Wed, Oct 7, 2009 at 3:43 AM, Andrew Bell <andrew.bell@xxxxxxxx> wrote: >> Matt and list: >> >> Thanks for pointer to Ceranic et al (1998), a paper which gives clear >> evidence that spontaneous otoacoustic emissions (SOAEs) and tinnitus are >> closely related. If SOAEs sound like tinnitus and behave like tinnitus, >> isn't it likely that they are (in some respect) tinnitus? >> >> If we are aiming to pinpoint tinnitus, then SOAEs offer the most direct >> tool, and Ceranic et al. support this idea. Their Table 5 shows that >> patients with head injury and tinnitus displayed 4.4 SOAEs per ear, compa= > red >> to 1.7 with normals and 0.25 with those having head injury without tinnit= > us. >> >> So did the head injury damage the cochlea and generate a tinnitus sensati= > on >> (via afferent pathways), or did the injury damage the brain, which respon= > ded >> by sending a signal to the cochlea (via efferent pathways)? As you say, t= > hat >> question is still very much open, but it would definitely repay some >> attention. >> >> >> Andrew. >> >> >> ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ >> Andrew Bell >> Research School of Biology (RSB) >> The Australian National University >> Canberra, ACT 0200, Australia >> T: +61 2 6125 5145 >> F: +61 2 6125 3808 >> andrew.bell@xxxxxxxx >> ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ >> >> >> >>> Further, tinnitus can also be induced by head injury [6]. In >>> this case, it is possible that the inner ear is damaged and >>> this causes a peripheral type of tinnitus, which again is a >>> cochlear amplifier dysfunction. Until we can successfully >>> trace this cause and develop methods such as cellular >>> regeneration possibly using stem cells - we can tinker and >>> experiment using all sorts of procedures to quash the >>> problem, but they will never be as sophisticated as actually >>> repairing the biology. >>> >>> >>> >>> [6] @xxxxxxxx{ceranic:1998, >>> =A0 author =3D {Ceranic, B.J. and Prasher, D.K. and Raglan, E. >>> and Luxon, L.M.}, >>> =A0 title =3D {{Tinnitus after head injury: evidence from >>> otoacoustic emissions}}, >>> =A0 journal =3D {Journal of Neurology, Neurosurgery \& Psychiatry}, >>> =A0 year =3D {1998}, >>> =A0 volume =3D {65}, >>> =A0 pages =3D {523--529}, >>> =A0 number =3D {4}, >>> =A0 publisher =3D {BMJ} >>> } >>> > > ------------------------------ > > Date: Wed, 7 Oct 2009 17:11:40 +0000 > From: Brian Gygi <bgygi@xxxxxxxx> > Subject: SOAEs and tinnitus > > ----=_vm_0011_W352665323_32197_1254935500 > Content-Type: text/plain; charset="us-ascii" > Content-Transfer-Encoding: quoted-printable > > > The problem is that there are also people (e.g., myself) who have tinnitu= > s but exhibit no SOAEs. Further, SOAE's don't really "sound" like tinnitu= > s - there are several different "sounds" of tinnitus, suchas ringing, "cr= > ickets" and very rarely a low frequency hum. I have crickets myself. This= > is the problem, as perviously stated, with grouping all disorders that k= > ind of behave like tinnitus under one heading, when they might have sever= > al different etiologies. > > Brian > > > -----Original Message----- > From: Andrew Bell [mailto:andrew.bell@xxxxxxxx > Sent: Wednesday, October 7, 2009 12:43 AM > To: AUDITORY@xxxxxxxx > Subject: Re: Technique can pinpoint tinnitus > > Matt and list:Thanks for pointer to Ceranic et al (1998), a paper which g= > ives clearevidence that spontaneous otoacoustic emissions (SOAEs) and tin= > nitus areclosely related. If SOAEs sound like tinnitus and behave like ti= > nnitus,isn't it likely that they are (in some respect) tinnitus?If we are= > aiming to pinpoint tinnitus, then SOAEs offer the most directtool, and C= > eranic et al. support this idea. Their Table 5 shows thatpatients with he= > ad injury and tinnitus displayed 4.4 SOAEs per ear, comparedto 1.7 with n= > ormals and 0.25 with those having head injury without tinnitus.So did the= > head injury damage the cochlea and generate a tinnitus sensation(via aff= > erent pathways), or did the injury damage the brain, which respondedby se= > nding a signal to the cochlea (via efferent pathways)? As you say, thatqu= > estion is still very much open, but it would definitely repay someattenti= > on.Andrew.~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~Andrew BellResearch Schoo= > l of Biology (RSB)The Australian National UniversityCanberra, ACT 0200, A= > ustraliaT: +61 2 6125 5145F: +61 2 6125 3808andrew.bell@xxxxxxxx~~~~~~~= > ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~> > Further, tinnitus can also be induced = > by head injury [6]. In > this case, it is possible that the inner ear is = > damaged and > this causes a peripheral type of tinnitus, which again is a= > > cochlear amplifier dysfunction. Until we can successfully > trace this= > cause and develop methods such as cellular > regeneration possibly using= > stem cells - we can tinker and > experiment using all sorts of procedure= > s to quash the > problem, but they will never be as sophisticated as actu= > ally > repairing the biology.> > > > [6] @xxxxxxxx{ceranic:1998,> author =3D= > {Ceranic, B.J. and Prasher, D.K. and Raglan, E. > and Luxon, L.M.},> tit= > le =3D {{Tinnitus after head injury: evidence from > otoacoustic emission= > s}},> journal =3D {Journal of Neurology, Neurosurgery \& Psychiatry},> ye= > ar =3D {1998},> volume =3D {65},> pages =3D {523--529},> number =3D {4},>= > publisher =3D {BMJ}> }> > > ----=_vm_0011_W352665323_32197_1254935500 > Content-Type: text/html; charset="us-ascii" > Content-Transfer-Encoding: quoted-printable > > <html><div> <br>The problem is that there are also people (e.g., myself) = > who have tinnitus but exhibit no SOAEs. Further, SOAE's don't reall= > y "sound" like tinnitus - there are several different "sounds" of tinnitu= > s, suchas ringing, "crickets" and very rarely a low frequency hum. = > I have crickets myself. This is the problem, as perviously stated, = > with grouping all disorders that kind of behave like tinnitus under one h= > eading, when they might have several different etiologies.<br><br>Brian <= > br><br></div> > <blockquote style=3D"border-left: 2px solid rgb(0, 0, 255); padding-left:= > 5px; margin-left: 5px; margin-right: 0px;"><font face=3D"Tahoma" size=3D= > "2">-----Original Message-----<br><b>From:</b> Andrew Bell [mailto:andrew= > .bell@xxxxxxxx<br><b>Sent:</b> Wednesday, October 7, 2009 12:43 AM<br>= > <b>To:</b> AUDITORY@xxxxxxxx<br><b>Subject:</b> Re: Technique can = > pinpoint tinnitus<br><br></font>Matt and list: > > Thanks for pointer to Ceranic et al (1998), a paper which gives clear > evidence that spontaneous otoacoustic emissions (SOAEs) and tinnitus are > closely related. If SOAEs sound like tinnitus and behave like tinnitus, > isn't it likely that they are (in some respect) tinnitus? > > If we are aiming to pinpoint tinnitus, then SOAEs offer the most direct > tool, and Ceranic et al. support this idea. Their Table 5 shows that > patients with head injury and tinnitus displayed 4.4 SOAEs per ear, compa= > red > to 1.7 with normals and 0.25 with those having head injury without tinnit= > us. > > > So did the head injury damage the cochlea and generate a tinnitus sensati= > on > (via afferent pathways), or did the injury damage the brain, which respon= > ded > by sending a signal to the cochlea (via efferent pathways)? As you say, t= > hat > question is still very much open, but it would definitely repay some > attention. > > > Andrew. > > > ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ > Andrew Bell > Research School of Biology (RSB) > The Australian National University > Canberra, ACT 0200, Australia > T: +61 2 6125 5145 > F: +61 2 6125 3808 > andrew.bell@xxxxxxxx > ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ > > > > > > > Further, tinnitus can also be induced by head injury [6]. In > > this case, it is possible that the inner ear is damaged and > > this causes a peripheral type of tinnitus, which again is a > > cochlear amplifier dysfunction. Until we can successfully > > trace this cause and develop methods such as cellular > > regeneration possibly using stem cells - we can tinker and > > experiment using all sorts of procedures to quash the > > problem, but they will never be as sophisticated as actually > > repairing the biology. > > > > > > > > [6] @xxxxxxxx{ceranic:1998, > > author =3D {Ceranic, B.J. and Prasher, D.K. and Raglan, E. > > and Luxon, L.M.}, > > title =3D {{Tinnitus after head injury: evidence from > > otoacoustic emissions}}, > > journal =3D {Journal of Neurology, Neurosurgery \& Psychiatry}= > , > > year =3D {1998}, > > volume =3D {65}, > > pages =3D {523--529}, > > number =3D {4}, > > publisher =3D {BMJ} > > } > > > </blockquote></html> > > ----=_vm_0011_W352665323_32197_1254935500-- > > ------------------------------ > > Date: Wed, 7 Oct 2009 22:32:49 +0200 > From: Pierre Divenyi <pdivenyi@xxxxxxxx> > Subject: Re: SOAEs and tinnitus > >> This message is in MIME format. Since your mail reader does not understand > this format, some or all of this message may not be legible. > > --B_3337799571_4462796 > Content-type: text/plain; > charset="ISO-8859-1" > Content-transfer-encoding: quoted-printable > > I stopped doing OAE research in the late 80=B9s, but the accepted statistics > then was that the 2x2 matrix of Tinnitus-y-or-n vs. SOAO-y-or-n had 4 almos= > t > equal cells. Has this statistic changed indicating now a significant > correlation? > > -Pierre > > > On 10/7/09 7:11 PM, "Brian Gygi" <bgygi@xxxxxxxx> wrote: > >> =20 >> The problem is that there are also people (e.g., myself) who have tinnitu= > s but >> exhibit no SOAEs. Further, SOAE's don't really "sound" like tinnitus - t= > here >> are several different "sounds" of tinnitus, suchas ringing, "crickets" an= > d >> very rarely a low frequency hum. I have crickets myself. This is the >> problem, as perviously stated, with grouping all disorders that kind of b= > ehave >> like tinnitus under one heading, when they might have several different >> etiologies. >> =20 >> Brian=20 >> =20 >>> -----Original Message----- >>> From: Andrew Bell [mailto:andrew.bell@xxxxxxxx >>> Sent: Wednesday, October 7, 2009 12:43 AM >>> To: AUDITORY@xxxxxxxx >>> Subject: Re: Technique can pinpoint tinnitus >>> =20 >>> Matt and list: Thanks for pointer to Ceranic et al (1998), a paper which >>> gives clear evidence that spontaneous otoacoustic emissions (SOAEs) and >>> tinnitus are closely related. If SOAEs sound like tinnitus and behave li= > ke >>> tinnitus, isn't it likely that they are (in some respect) tinnitus? If w= > e are >>> aiming to pinpoint tinnitus, then SOAEs offer the most direct tool, and >>> Ceranic et al. support this idea. Their Table 5 shows that patients with= > head >>> injury and tinnitus displayed 4.4 SOAEs per ear, compared to 1.7 with no= > rmals >>> and 0.25 with those having head injury without tinnitus. So did the head >>> injury damage the cochlea and generate a tinnitus sensation (via afferen= > t >>> pathways), or did the injury damage the brain, which responded by sendin= > g a >>> signal to the cochlea (via efferent pathways)? As you say, that question= > is >>> still very much open, but it would definitely repay some attention. Andr= > ew. >>> ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Andrew Bell Research School of Bi= > ology >>> (RSB) The Australian National University Canberra, ACT 0200, Australia T= > : +61 >>> 2 6125 5145 F: +61 2 6125 3808 andrew.bell@xxxxxxxx >>> ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ > > Further, tinnitus can also be >>> induced by head injury [6]. In > this case, it is possible that the inne= > r ear >>> is damaged and > this causes a peripheral type of tinnitus, which again = > is a >>>> cochlear amplifier dysfunction. Until we can successfully > trace this >>> cause and develop methods such as cellular > regeneration possibly using= > stem >>> cells - we can tinker and > experiment using all sorts of procedures to = > quash >>> the > problem, but they will never be as sophisticated as actually > >>> repairing the biology. > > > > [6] @xxxxxxxx{ceranic:1998, > author =3D >>> {Ceranic, B.J. and Prasher, D.K. and Raglan, E. > and Luxon, L.M.}, > = > title >>> =3D {{Tinnitus after head injury: evidence from > otoacoustic emissions}},= > > >>> journal =3D {Journal of Neurology, Neurosurgery \& Psychiatry}, > year =3D >>> {1998}, > volume =3D {65}, > pages =3D {523--529}, > number =3D {4}, > >>> publisher =3D {BMJ} > } > >> =20 > > > > --B_3337799571_4462796 > Content-type: text/html; > charset="ISO-8859-1" > Content-transfer-encoding: quoted-printable > > <HTML> > <HEAD> > <TITLE>Re: SOAEs and tinnitus</TITLE> > </HEAD> > <BODY> > <FONT FACE=3D"Verdana, Helvetica, Arial"><SPAN STYLE=3D'font-size:12.0px'>I sto= > pped doing OAE research in the late 80’s, but the accepted statistics = > then was that the 2x2 matrix of Tinnitus-y-or-n vs. SOAO-y-or-n had 4 almost= > equal cells. Has this statistic changed indicating now a significant correl= > ation?<BR> > <BR> > -Pierre<BR> > <BR> > <BR> > On 10/7/09 7:11 PM, "Brian Gygi" <bgygi@xxxxxxxx> wrote:<B= > R> > <BR> > </SPAN></FONT><BLOCKQUOTE><FONT FACE=3D"Verdana, Helvetica, Arial"><SPAN STYL= > E=3D'font-size:12.0px'> <BR> > The problem is that there are also people (e.g., myself) who have tinnitus = > but exhibit no SOAEs. Further, SOAE's don't really "sound" l= > ike tinnitus - there are several different "sounds" of tinnitus, s= > uchas ringing, "crickets" and very rarely a low frequency hum. &nb= > sp;I have crickets myself. This is the problem, as perviously stated, = > with grouping all disorders that kind of behave like tinnitus under one head= > ing, when they might have several different etiologies.<BR> > <BR> > Brian <BR> > <BR> > </SPAN></FONT><BLOCKQUOTE><SPAN STYLE=3D'font-size:12.0px'><FONT FACE=3D"Tahoma= > ">-----Original Message-----<BR> > <B>From:</B> Andrew Bell [<a href=3D"mailto:andrew.bell@xxxxxxxx">mailto:a= > ndrew.bell@xxxxxxxx</a><BR> > <B>Sent:</B> Wednesday, October 7, 2009 12:43 AM<BR> > <B>To:</B> AUDITORY@xxxxxxxx<BR> > <B>Subject:</B> Re: Technique can pinpoint tinnitus<BR> > <BR> > </FONT><FONT FACE=3D"Verdana, Helvetica, Arial">Matt and list: Thanks for poi= > nter to Ceranic et al (1998), a paper which gives clear evidence that sponta= > neous otoacoustic emissions (SOAEs) and tinnitus are closely related. If SOA= > Es sound like tinnitus and behave like tinnitus, isn't it likely that they a= > re (in some respect) tinnitus? If we are aiming to pinpoint tinnitus, then S= > OAEs offer the most direct tool, and Ceranic et al. support this idea. Their= > Table 5 shows that patients with head injury and tinnitus displayed 4.4 SOA= > Es per ear, compared to 1.7 with normals and 0.25 with those having head inj= > ury without tinnitus. So did the head injury damage the cochlea and generate= > a tinnitus sensation (via afferent pathways), or did the injury damage the = > brain, which responded by sending a signal to the cochlea (via efferent path= > ways)? As you say, that question is still very much open, but it would defin= > itely repay some attention. Andrew. ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ A= > ndrew Bell Research School of Biology (RSB) The Australian National Universi= > ty Canberra, ACT 0200, Australia T: +61 2 6125 5145 F: +61 2 6125 3808 andre= > w.bell@xxxxxxxx ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ > > Further, = > tinnitus can also be induced by head injury [6]. In > this case, it is po= > ssible that the inner ear is damaged and > this causes a peripheral type = > of tinnitus, which again is a > cochlear amplifier dysfunction. Until we = > can successfully > trace this cause and develop methods such as cellular = > > regeneration possibly using stem cells - we can tinker and > experim= > ent using all sorts of procedures to quash the > problem, but they will n= > ever be as sophisticated as actually > repairing the biology. > > &= > gt; > [6] @xxxxxxxx{ceranic:1998, > author =3D {Ceranic, B.J.= > and Prasher, D.K. and Raglan, E. > and Luxon, L.M.}, > ti= > tle =3D {{Tinnitus after head injury: evidence from > otoacoustic emissions= > }}, > journal =3D {Journal of Neurology, Neurosurgery \& Ps= > ychiatry}, > year =3D {1998}, > volume =3D {65}, &= > gt; pages =3D {523--529}, > number =3D {4}, > &nbs= > p; publisher =3D {BMJ} > } > <BR> > </FONT></SPAN></BLOCKQUOTE><SPAN STYLE=3D'font-size:12.0px'><FONT FACE=3D"Verda= > na, Helvetica, Arial"><BR> > </FONT></SPAN></BLOCKQUOTE><SPAN STYLE=3D'font-size:12.0px'><FONT FACE=3D"Verda= > na, Helvetica, Arial"><BR> > </FONT></SPAN> > </BODY> > </HTML> > > > --B_3337799571_4462796-- > > ------------------------------ > > Date: Wed, 7 Oct 2009 21:23:36 -0400 > From: Jim Ballas <james.ballas@xxxxxxxx> > Subject: Re: Technique can pinpoint tinnitus > > Another cause of tinnitus is a Vestibular Schwannoma (Acoustic=20 > Neuroma). In my case the tinnitus, together with partial unilateral=20 > hearing loss, was the first indication of the tumor. This cause affects=20 > the third site, the auditory pathway, where M=F8ller says abnormal neura= > l=20 > activity can be causing tinnitus. So IMHO, classifying mechanisms of=20 > tinnitus as either peripheral or central, while better than one=20 > mechanism, is still a simplification. > Jim Ballas >> Date: Tue, 6 Oct 2009 14:30:39 -0400 >> From: Didier Depireux <depireux@xxxxxxxx> >> Subject: Re: Technique can pinpoint tinnitus >> >> It's hard to form an opinion from a release from a PR office. But a >> lot of papers on imaging and/or treatment of tinnitus neglect to >> mention the etiology of the tinnitus. One can acquire permanent >> tinnitus from drugs like quinine, cancer drugs like most of the >> -platins, noise exposure, blunt trauma, or related to the onset of >> M=3DE9ni=3DE8re's. While the behavioral manifestation is the same, ther= > e is no >> good argument that all these causes lead to the same underlying >> changes in the auditory pathway. So any paper that claims to have >> found that a "Technique can pinpoint tinnitus" is bound to be met with >> some measure of healthy doubt. >> >> To quote Aage M=F8ller in his "Tinnitus: presence and future" paper, >> >> It is unfortunate that the same name, tinnitus, is used for so many >> different disorders. This hampers both understanding of the >> pathophysiology of tinnitus and the treatment because it implies that >> it is possible to find _the_ cause of tinnitus and _the_ treatment for >> tinnitus. >> >> He goes on to say: >> >> Disorders of the vestibular system was earlier in the same category, >> but the introduction of specific names such as benign positional >> paroxysmal nystagmus (BPPN) and disabling positional vertigo (DPV) has >> greatly improved treatment and understanding of the causes of various >> symptoms from the vestibular system. >> >> In related news, some Irish teenagers have gotten a 99% cure rate by >> playing to tinnitus sufferers a "low hum [that] might straighten out >> those bent cochlear hairs" >> http://www.scientificamerican.com/podcast/episode.cfm?id=3D3Dteen-inven= > tors-f=3D >> ight-tinnitus-09-09-28 >> >> Didier >> >> Didier A Depireux depireux@xxxxxxxx >> Inst. for Systems Research http://theearlab.org >> School of Engineering Ph: 410-925-6546 >> U Md College Park MD 20742 USA >> Adjunct, BioEngineering >> >> >> =20 > > Date: Tue, 6 Oct 2009 14:30:39 -0400 > From: Didier Depireux <depireux@xxxxxxxx> > Subject: Re: Technique can pinpoint tinnitus > > It's hard to form an opinion from a release from a PR office. But a > lot of papers on imaging and/or treatment of tinnitus neglect to > mention the etiology of the tinnitus. One can acquire permanent > tinnitus from drugs like quinine, cancer drugs like most of the > -platins, noise exposure, blunt trauma, or related to the onset of > M=3DE9ni=3DE8re's. While the behavioral manifestation is the same, there = > is no > good argument that all these causes lead to the same underlying > changes in the auditory pathway. So any paper that claims to have > found that a "Technique can pinpoint tinnitus" is bound to be met with > some measure of healthy doubt. > > To quote Aage M=3DF8ller in his "Tinnitus: presence and future" paper, > > It is unfortunate that the same name, tinnitus, is used for so many > different disorders. This hampers both understanding of the > pathophysiology of tinnitus and the treatment because it implies that > it is possible to find _the_ cause of tinnitus and _the_ treatment for > tinnitus. > > He goes on to say: > > Disorders of the vestibular system was earlier in the same category, > but the introduction of specific names such as benign positional > paroxysmal nystagmus (BPPN) and disabling positional vertigo (DPV) has > greatly improved treatment and understanding of the causes of various > symptoms from the vestibular system. > > In related news, some Irish teenagers have gotten a 99% cure rate by > playing to tinnitus sufferers a "low hum [that] might straighten out > those bent cochlear hairs" > http://www.scientificamerican.com/podcast/episode.cfm?id=3D3Dteen-invento= > rs-f=3D > ight-tinnitus-09-09-28 > > Didier > > Didier A Depireux depireux@xxxxxxxx > Inst. for Systems Research http://theearlab.org > School of Engineering Ph: 410-925-6546 > U Md College Park MD 20742 USA > Adjunct, BioEngineering > > ------------------------------ > > End of AUDITORY Digest - 6 Oct 2009 to 7 Oct 2009 (#2009-230) > ************************************************************* >