Subject: Re: Individual Differences in Outer Hair Cell Function From: Pierre Divenyi <pdivenyi@xxxxxxxx> Date: Sat, 17 Mar 2007 15:17:24 -0700 List-Archive:<http://lists.mcgill.ca/scripts/wa.exe?LIST=AUDITORY>Jim, Good luck with your search. One thing though: since you are talking about cross-species, don't forget about musicians who, I should know, represent a species on their own. Pierre At 09:36 AM 3/17/2007, James D. Miller wrote: >List, > > Does anyone know of published evidence that people with normal > densities (#OHC/mm) of normal outer hairs (they look normal, have > all their stereo cilia and mitochondria etc), differ in function? > That is, do some with normal outer hair cells have better cochlear > amplifiers with sharper tuning than others with the same densities > (#OHC/mm) of completely normal outer hair cells? I would be even > interested in cross-species comparisons, if they make sense, since > so much of what we know about hearing is, in fact, based on > cross-species comparisons. > > I ask because a reviewer of a recent grant proposal of mine > appeared to think that everybody should know that some people have > better outer hair cells than others, even when the OHC density per > unit length is the same and when there is no sign of injury or > deficit. I suppose it's a possiblity, but is there any evidence of any kind? > > Jim > >-- >James D. Miller, Ph.D. >Principal Scientist >Communication Disorders Technology, Inc. >Indiana University Research Park >501 N. Morton Street Suite 215 >Bloomington, IN 47404 >Business Phone: (812)336-1766 >Cingular Cell Phone: (812)360-0612