Re: Individual Differences in Outer Hair Cell Function

[Pierre Divenyi <pdivenyi@xxxxxxxxx>]

Jim,

Good luck with your search. One thing though: since you are talking 
about cross-species, don't forget about musicians who, I should know, 
represent a species on their own.

Pierre

At 09:36 AM 3/17/2007, James D. Miller wrote:
> List,
>
>  Does anyone know of published evidence that people with normal 
> densities (#OHC/mm) of normal outer hairs (they look normal, have 
> all their stereo cilia and mitochondria etc), differ in function? 
> That is, do some with normal outer hair cells have better cochlear 
> amplifiers with sharper tuning than others with the same densities 
> (#OHC/mm) of completely normal outer hair cells?  I would be even 
> interested in cross-species comparisons, if they make sense, since 
> so much of what we know about hearing is, in fact, based on 
> cross-species comparisons.
>
>  I ask because a reviewer of a recent grant proposal of mine 
> appeared to think that everybody should know that some people have 
> better outer hair cells than others, even when the OHC density per 
> unit length is the same and when there is no sign of injury or 
> deficit. I suppose it's a possiblity, but is there any evidence of any kind?
>
>    Jim
>
> --
> James D. Miller, Ph.D.
> Principal Scientist
> Communication Disorders Technology, Inc.
> Indiana University Research Park
> 501 N. Morton Street Suite 215
> Bloomington, IN 47404
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